(Previous | Contents
| Next)
LAMARC Documentation: Future
Upcoming Features for LAMARC
Here are some features we plan to add to LAMARC, both
in the next release, and in the more distant future.
 
-  Natural selection.  We will estimate selection parameters by
treating the selected and non-selected alleles as defining "populations"
with "migration" due to mutation and recombination allowing haplotypes or
sections of haplotypes to move between the "populations".
-  Ascertainment bias.  We will deal with ascertainment bias (for example,
the preferential choice of diseased individuals in case/control studies)
by modeling diseased and healthy as "populations".
-  Recombination hotspot estimation.  We will estimate the presence of
recombination hot or cold regions.  (Chul Joo Kang is currently working on
implementing this in Recombine.)
-  Alternative models for growth.  Our current model of
continuously exponential growth is inadequate for certain populations, and
we plan to add both linear and stair-step models of growth (and shrinkage).
-  Sequential sampling.  Sometimes it is possible to collect or
obtain data from multiple generations of your organism (HIV is a good
candidate for this).  If the mutation rate is known, it is theoretically
possible to include this data in a LAMARC-type analysis, and we plan to
allow this.
(Previous | Contents
| Next)